

| 货号 | HB935021 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Human BDNF Recombinant Protein (Tag Free) (HB935021) expressed in Mammalian cells. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | P23560 |
| 蛋白长度 | His129-Arg247 |
| 应用 | ELISA, Functional assay |
| 种属 | Homo sapiens (Human) |
| 生物活性 | Determined by the dose-dependent proliferation of C6 cell sand is typically between 0.5-1.5 ug/mL.Corresponding to a specific Activity of 1 x 103 units/mg. |
| 性质 | Recombinant |
| 内毒素水平 | <0.01 EU/ug |
| 纯度 | >95% as determined by SDS-PAGE. |
| 预测分子量 | 13.5 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol, 0.01% Tween 80, pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Abrineurin, BDNF, Brain-derived neurotrophic factor, Neurotrophic factor BDNF, Neurotrophic factor BDNF precursor form, proBDNF |
| 背景 | Neurotrophic factor BDNF precursor form is a ~27 kDa protein. Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. 1. Mowla, SJ. et al. (2001) The Journal of biological chemistry 276, 12660-6. PMID: 11152678 |
| Note | For research use only. |

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