

| 货号 | HV658031 |
|---|---|
| 品牌 | abinScience |
| 描述 |
GMP Grade Human IL-21 (Human Fc) (HV658031) expressed in Mammalian cells. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | Q9HBE4 |
| 蛋白长度 | His25-Ser162 |
| 应用 | ELISA, Functional assay |
| 种属 | Homo sapiens (Human) |
| 生物活性 | Measured by its ability to enhance IFN-gamma secretion in NK-92 human natural killer lymphoma cells. The ED50 for this effect is ≤ 20 ng/mL. |
| 性质 | Recombinant |
| 内毒素水平 | <0.01 EU/ug |
| 纯度 | >95% as determined by SDS-PAGE. |
| 预测分子量 | 41.9 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol, 0.01% Tween 80, pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | IL-21, IL21, Interleukin-21, Za11 |
| 背景 | Interleukin-21 (IL-21,Interleukin-21,IL21,Za11) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection. 1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504 2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704 |
| Note | For research use only. |

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