

| 货号 | HF877011 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Human PDGF-B Recombinant Protein (Tag Free) (HF877011) expressed in Mammalian cells. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | P01127 |
| 蛋白长度 | Ser82-Thr190 |
| 应用 | ELISA, Functional assay |
| 种属 | Homo sapiens (Human) |
| 生物活性 | Measured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is ≤5 ng/mL. |
| 性质 | Recombinant |
| 内毒素水平 | <0.01 EU/ug |
| 纯度 | >95% as determined by SDS-PAGE. |
| 预测分子量 | 12.2 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a 0.22 μm-filtered solution containing PBS,5% Mannitol, 0.01% Tween 80, pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Becaplermin, PDGF subunit B, PDGF-2, PDGF2, PDGFB, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, Proto-oncogene c-Sis, SIS |
| 背景 | Platelet-derived growth factor subunit B (PDGFB) is a ~27 kDa protein. Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. 1. Vanlandewijck, M. et al. (2015) PloS one 10, e0143407. PMID: 26599395 |
| Note | For research use only. |

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