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InVivoMAb Anti-Mouse B7-H4 Antibody (Iv0257) (MV721010)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号MV721010
品牌abinScience
描述
InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257) [Iv0257] (MV721010) is a mouse monoclonal antibody detecting V-set domain containing T-cell activation inhibitor 1 in ELISA, FCM, Neutralization. Suitable for Mouse.
Highlights
  • Multi-Application — Validated across multiple applications.
  • Flow Cytometry — Validated for flow cytometry applications.
种属反应性Mouse
应用ELISA, FCM, Neutralization
宿主Mouse
同种型IgG2a, kappa
克隆号Iv0257
克隆类型Monoclonal
经测试应用FCM
靶标V-set domain containing T-cell activation inhibitor 1, B7 homolog 4, B7-H4, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, Vtcn1, B7h4
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q7TSP5
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

V-set domain containing T-cell activation inhibitor 1 (VTCN1/B7-H4) is a ~30 kDa protein. Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Flow CytoMetry

    Flow-cytometry using anti-human VTCN1 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human VTCN1 monoclonal antibody (Catalog: MV721010) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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