InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271) (CF879010)

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100ug
1mg

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概述
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产品说明书

概述

货号	CF879010
品牌	abinScience
描述	InVivoMAb Anti-Dog TNFa/TNF-alpha Antibody (Iv0271) [Iv0271] (CF879010) is a dog monoclonal antibody detecting TNF in Blocking, ELISA, FCM. Suitable for Dog. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
种属反应性	Canine
应用	Blocking, ELISA, FCM
宿主	Canine
同种型	IgG1, kappa
克隆号	Iv0271
克隆类型	Monoclonal
靶标	TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P51742
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Tumor necrosis factor (TNFa/TNF-alpha) is a ~25 kDa protein. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. TNFa is the therapeutic target of adalimumab (Humira).
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Dog TNFa/TNF-alpha Antibody (Iv0271)
Bioactivity

Detects recombinant dog TNFa/TNF-alpha (Catalog No: CF879011) in indirect ELISA

参考文献

产品说明书

InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271) (CF879010)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Canine TNF-alpha Antibody (Iv0271) (CF879010)

概述

图片

参考文献

产品说明书

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