InVivoMAb Anti-Mouse TIGIT Antibody (10A7) (ARO-A12959)

概述
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概述

货号	ARO-A12959
品牌	ProteoGenix
描述	InVivoMAb Anti-Mouse TIGIT Antibody (10A7) [10A7] (ARO-A12959) is a mouse monoclonal antibody detecting T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, Tigit, Vstm3 in ELISA, FCM, FuncS. Suitable for Mouse. Highlights Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background. Multi-Application — Validated across multiple applications.
种属反应性	Mouse
应用	ELISA, FCM, FuncS
宿主	Mouse
同种型	IgG2a, kappa
克隆号	10A7
克隆类型	Monoclonal
靶标	T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, Tigit, Vstm3
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P86176
状态	Liquid
保存溶液	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is a ~26 kDa protein. Inhibitory receptor that plays a role in the modulation of immune responses. Suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. Upon binding to its ligands PVR/CD155 or NECTIN2/CD112, which are expressed on antigen-presenting cells, sends inhibitory signals to the T-cell or NK cell. Mechanistically, interaction with ligand leads to phosphorylation of the cytoplasmic tail by Src family tyrosine kinases such as FYN or LCK, allowing subsequent binding to adapter GRB2 and SHIP1/INPP5D. In turn, inhibits PI3K and MAPK signaling cascades.
Note	For research use only. Not suitable for clinical or therapeutic use.

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公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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InVivoMAb Anti-Mouse TIGIT Antibody (10A7) (ARO-A12959)

概述

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参考文献

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重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Mouse TIGIT Antibody (10A7) (ARO-A12959)

概述

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参考文献

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