InVivoMAb Anti-Human BMP4 Antibody (6H4) (ARO-A13011)

概述
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参考文献

概述

货号	ARO-A13011
品牌	ProteoGenix
描述	InVivoMAb Anti-Human BMP4 Antibody (6H4) [6H4] (ARO-A13011) is a mouse monoclonal antibody detecting Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B, BMP4, BMP2B, DVR4 in ELISA, Neutralization. Suitable for Human. Highlights Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, Neutralization
宿主	Mouse
同种型	IgG2a, kappa
克隆号	6H4
克隆类型	Monoclonal
靶标	Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B, BMP4, BMP2B, DVR4
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P12644
状态	Liquid
保存溶液	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Bone morphogenetic protein 4 (BMP4) is a ~46 kDa protein. Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. 1. Rezzola, S. et al. (2019) Angiogenesis 22, 521-533. PMID: 31363885 2. Rege, J. et al. (2015) Endocrinology 156, 2530-40. PMID: 25868050 3. ten Dijke, P. et al. (1994) The Journal of biological chemistry 269, 16985-8. PMID: 8006002 4. Jin, X. et al. (2017) Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 44, 1616-1628. PMID: 29212066
Note	For research use only. Not suitable for clinical or therapeutic use.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human BMP4 Antibody (6H4) (ARO-A13011)

概述

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参考文献

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重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Human BMP4 Antibody (6H4) (ARO-A13011)

概述

图片

参考文献

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