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InVivoMAb Anti-Human CD283/TLR3 Antibody (Iv0179) (ARO-A13144)

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概述
货号ARO-A13144
品牌ProteoGenix
描述
InVivoMAb Anti-Human CD283/TLR3 Antibody (Iv0179) [Iv0179] (ARO-A13144) is a mouse monoclonal antibody detecting TLR3, CD283, Toll-like receptor 3 in Neutralization. Suitable for Human.
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Validated for Neutralization — Optimized for consistent performance.
种属反应性Human
应用Neutralization
宿主Mouse
同种型IgG2a, kappa
克隆号Iv0179
克隆类型Monoclonal
靶标TLR3, CD283, Toll-like receptor 3
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O15455
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Toll-like receptor 3 (CD283/TLR3) is a ~103 kDa protein. Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.

NoteFor research use only. Not suitable for clinical or therapeutic use.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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