InVivoMAb Anti-HPV B19/B19V VP1/Coat protein VP1 (Iv0008) (ARO-A13365)

概述
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参考文献

概述

货号	ARO-A13365
品牌	ProteoGenix
描述	InVivoMAb Anti-HPV B19/B19V VP1/Coat protein VP1 (Iv0008) (ARO-A13365) Purity: >95% as determined by SDS-PAGE.. Highlights Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human parvovirus B19 (strain HV) (HPV B19), Human parvovirus B19 (isolate AU) (HPV B19)
应用	ELISA, Neutralization
宿主	Human
同种型	IgG1, kappa
克隆号	Iv0008
克隆类型	Monoclonal
靶标	Minor capsid protein VP1, 3.1.1.4, Coat protein VP1, vp
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q9PZT0, P07299
状态	Liquid
保存溶液	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Minor capsid protein VP1 (Coatprotein VP1) is a ~86 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 20 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA (Probable). Binds to erythroid progenitor cells expressing high levels of P antigen and uses host ITGA5-ITGB1 and XRCC5/Ku80 autoantigen as coreceptors on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. 1. Kaufmann, B. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 11628-33. PMID: 15289612 2. Weigel-Kelley, KA. et al. (2003) Blood 102, 3927-33. PMID: 12907437 3. Munakata, Y. et al. (2005) Blood 106, 3449-56. PMID: 16076874 4. Brown, KE. et al. (1993) Science (New York, N.Y.) 262, 114-7. PMID: 8211117 5. Quattrocchi, S. et al. (2012) Journal of virology 86, 9274-84. PMID: 22718826 6. Ros, C. et al. (2006) Journal of virology 80, 12017-24. PMID: 17020940 7. Zádori, Z. et al. (2001) Developmental cell 1, 291-302. PMID: 11702787
Note	For research use only. Not suitable for clinical or therapeutic use.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-HPV B19/B19V VP1/Coat protein VP1 (Iv0008) (ARO-A13365)

概述

图片

参考文献

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-HPV B19/B19V VP1/Coat protein VP1 (Iv0008) (ARO-A13365)

概述

图片

参考文献

相关产品推荐

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