

| 货号 | ARO-A13291 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
InVivoMAb Anti-Human CCL17/TARC (Iv0083) [Iv0083] (ARO-A13291) is a human monoclonal antibody detecting Thymus and activation-regulated chemokine, SCYA17, TARC, Small-inducible cytokine A17, C-C motif chemokine 17, CC chemokine TARC, CCL17 in ELISA, Neutralization. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, Neutralization |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | Iv0083 |
| 克隆类型 | Monoclonal |
| 靶标 | Thymus and activation-regulated chemokine, SCYA17, TARC, Small-inducible cytokine A17, C-C motif chemokine 17, CC chemokine TARC, CCL17 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q92583 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. 1. Imai, T. et al. (1996) The Journal of biological chemistry 271, 21514-21. PMID: 8702936 2. Imai, T. et al. (1997) The Journal of biological chemistry 272, 15036-42. PMID: 9169480 3. Garlisi, CG. et al. (1999) European journal of immunology 29, 3210-5. PMID: 10540332 4. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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