

| 货号 | ARO-A13323 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
InVivoMAb Anti-Human LTA/TNF-beta (Iv0051) [Iv0051] (ARO-A13323) is a human monoclonal antibody detecting TNF-beta, TNFSF1, Tumor necrosis factor ligand superfamily member 1, LTA, Lymphotoxin-alpha, LT-alpha, TNFB in ELISA, FCM, Neutralization. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, FCM, Neutralization |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | Iv0051 |
| 克隆类型 | Monoclonal |
| 靶标 | TNF-beta, TNFSF1, Tumor necrosis factor ligand superfamily member 1, LTA, Lymphotoxin-alpha, LT-alpha, TNFB |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P01374 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Lymphotoxin-alpha (LTA/TNF-beta) is a ~22 kDa protein. Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. 1. Mauri, DN. et al. (1998) Immunity 8, 21-30. PMID: 9462508 2. Sudhamsu, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 19896-901. PMID: 24248355 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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