Anti-Human RECQL5 Recombinant Nanobody (SAA1003) (HF650023)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HF650023

品牌

abinScience

描述

Anti-Human RECQL5 Nanobody (SAA1003) [SAA1003] (HF650023) is a alpaca monoclonal antibody detecting RECQL5 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

克隆类型

Monoclonal

同种型

VHH-8His-Cys-tag

克隆号

SAA1003

靶标

RECQ5, RecQ protein-like 5, RecQ5, DNA helicase, RecQ-like type 5, ATP-dependent DNA helicase Q5, RECQL5

内毒素水平

< 10 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

O94762

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

ATP-dependent DNA helicase Q5 (RECQL5) is a ~108 kDa protein. DNA helicase that plays an important role in DNA replication, transcription and repair. Probably unwinds DNA in a 3'-5' direction (Probable). Binds to the RNA polymerase II subunit POLR2A during transcription elongation and suppresses transcription-associated genomic instability. Also associates with POLR1A and enforces the stability of ribosomal DNA arrays. Plays an important role in mitotic chromosome separation after cross-over events and cell cycle progress.

1. Blundred, R. et al. (2010) DNA repair 9, 964-75. PMID: 20643585

2. Tadokoro, T. et al. (2012) Molecular biology of the cell 23, 4273-85. PMID: 22973052

3. Newman, JA. et al. (2017) Nucleic acids research 45, 4231-4243. PMID: 28100692

4. Islam, MN. et al. (2010) Molecular and cellular biology 30, 2460-72. PMID: 20231364

5. Urban, V. et al. (2016) The Journal of cell biology 214, 401-15. PMID: 27502483

6. Ramamoorthy, M. et al. (2012) Nucleic acids research 40, 1621-35. PMID: 22013166

7. Di Marco, S. et al. (2017) Molecular cell 66, 658-671.e8. PMID: 28575661

8. Ramamoorthy, M. et al. (2013) Carcinogenesis 34, 2218-30. PMID: 23715498

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human RECQL5 Nanobody (SAA1003)

参考文献

产品说明书

Anti-Human RECQL5 Recombinant Nanobody (SAA1003).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RECQL5 Recombinant Nanobody (SAA1003) (HF650023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RECQL5 Recombinant Nanobody (SAA1003) (HF650023)

概述

图片

参考文献

产品说明书

相关产品推荐

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