

| 货号 | HY157013 | ||||||
|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||
| 描述 |
Anti-Human TK1 Nanobody (SAA1373) [SAA1373] (HY157013) is a alpaca monoclonal antibody detecting TK1 in DB, ELISA, FCM, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||
| 应用 | DB, ELISA, FCM, WB | ||||||
| 宿主 | Alpaca | ||||||
| 克隆类型 | Monoclonal | ||||||
| 同种型 | VHH-8His-Cys-tag | ||||||
| 克隆号 | SAA1373 | ||||||
| 靶标 | Thymidine kinase, cytosolic, TK1 | ||||||
| 内毒素水平 | < 10 EU/mg as determined by LAL method. | ||||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||||
| 纯化方式 | Purified by Nickel column. | ||||||
| Accession号 | P04183 | ||||||
| 状态 | Liquid | ||||||
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 背景 | Thymidine kinase, cytosolic (TK1) is a ~25 kDa protein. Cell-cycle-regulated enzyme of importance in nucleotide metabolism. Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate. Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c-azido-3c-deoxythymidine (AZT). 1. Chang, ZF. et al. (1998) The Journal of biological chemistry 273, 12095-100. PMID: 9575153 2. Skovgaard, T. et al. (2012) The FEBS journal 279, 1777-87. PMID: 22385435 | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Human TK1 Nanobody (SAA1373)



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