Anti-Human SLC5A1 Recombinant Nanobody (SAA0963) (HB272013)

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50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HB272013

品牌

abinScience

描述

Anti-Human SLC5A1 Nanobody (SAA0963) [SAA0963] (HB272013) is a alpaca monoclonal antibody detecting SLC5A1 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

克隆类型

Monoclonal

同种型

VHH-8His-Cys-tag

克隆号

SAA0963

靶标

Solute carrier family 5 member 1, SLC5A1, High affinity sodium-glucose cotransporter, SGLT1, Sodium/glucose cotransporter 1, Na(+)/glucose cotransporter 1, NAGT

内毒素水平

< 10 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

P13866

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Sodium/glucose cotransporter 1 (SLC5A1) is a ~73 kDa protein. Electrogenic Na(+)-coupled sugar symporter that actively transports D-glucose or D-galactose at the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Has a primary role in the transport of dietary monosaccharides from enterocytes to blood. Responsible for the absorption of D-glucose or D-galactose across the apical brush-border membrane of enterocytes, whereas basolateral exit is provided by GLUT2. Additionally, functions as a D-glucose sensor in enteroendocrine cells, triggering the secretion of the incretins GCG and GIP that control food intake and energy homeostasis.

1. Hummel, CS. et al. (2011) American journal of physiology. Cell physiology 300, C14-21. PMID: 20980548

2. Han, L. et al. (2022) Nature 601, 274-279. PMID: 34880492

3. Kamitori, K. et al. (2022) Journal of molecular biology 434, 167464. PMID: 35077764

4. Martín, MG. et al. (1996) Nature genetics 12, 216-20. PMID: 8563765

5. Cui, W. et al. (2023) Nature communications 14, 2920. PMID: 37217492

6. Salker, MS. et al. (2017) Scientific reports 7, 12612. PMID: 28974690

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human SLC5A1 Nanobody (SAA0963)

参考文献

产品说明书

Anti-Human SLC5A1 Recombinant Nanobody (SAA0963).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC5A1 Recombinant Nanobody (SAA0963) (HB272013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC5A1 Recombinant Nanobody (SAA0963) (HB272013)

概述

图片

参考文献

产品说明书

相关产品推荐

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