Anti-Human LOX-1/OLR1 Recombinant Nanobody (SAA1291) (HX040013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HX040013

品牌

abinScience

描述

Anti-Human OLR1/LOX1 Nanobody (SAA1291) [SAA1291] (HX040013) is a alpaca monoclonal antibody detecting OLR1 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

克隆类型

Monoclonal

同种型

VHH-8His-Cys-tag

克隆号

SAA1291

靶标

C-type lectin domain family 8 member A, LOX-1, Ox-LDL receptor 1, Lectin-like oxidized LDL receptor 1, OLR1, Oxidized low-density lipoprotein receptor 1, Lectin-like oxLDL receptor 1, LOX1, CLEC8A, hLOX-1, Lectin-type oxidized LDL receptor 1

内毒素水平

< 10 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

P78380

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Oxidized low-density lipoprotein receptor 1 (OLR1/LOX-1) is a ~30 kDa protein. Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation.

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human OLR1/LOX1 Nanobody (SAA1291)

参考文献

产品说明书

Anti-Human LOX-1/OLR1 Recombinant Nanobody (SAA1291).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LOX-1/OLR1 Recombinant Nanobody (SAA1291) (HX040013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LOX-1/OLR1 Recombinant Nanobody (SAA1291) (HX040013)

概述

图片

参考文献

产品说明书

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