Anti-Human CD106/VCAM1 Recombinant Nanobody (SAA2055) (HB032013)

价格:

规格：

50ug
100ug
1mg

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HB032013

品牌

abinScience

描述

Anti-Human CD106/VCAM1 Nanobody (SAA2055) [SAA2055] (HB032013) is a alpaca monoclonal antibody detecting VCAM1 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

同种型

VHH-8His-Cys-tag

克隆号

SAA2055

克隆类型

Monoclonal

靶标

Vascular cell adhesion protein 1, VCAM1, CD106, INCAM-100, V-CAM 1, VCAM-1

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

P19320

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Vascular cell adhesion protein 1 (CD106/VCAM1) is a ~81 kDa protein. Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Also serves as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation.

1. Li, Y. et al. (2020) Journal of molecular cell biology 12, 190-201. PMID: 31310649

2. Taooka, Y. et al. (1999) The Journal of cell biology 145, 413-20. PMID: 10209034

3. Marchese, ME. et al. (2012) Biochemistry 51, 8235-46. PMID: 22970700

4. Pinho, S. et al. (2022) Nature cell biology 24, 290-298. PMID: 35210567

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human CD106/VCAM1 Nanobody (SAA2055)

参考文献

产品说明书

Anti-Human CD106/VCAM1 Recombinant Nanobody (SAA2055).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD106/VCAM1 Recombinant Nanobody (SAA2055) (HB032013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD106/VCAM1 Recombinant Nanobody (SAA2055) (HB032013)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价