Anti-Human CD19 Recombinant Nanobody (SAA2078) (HB996043)

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50ug
100ug
1mg

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概述
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参考文献
产品说明书

概述

货号

HB996043

品牌

abinScience

描述

Anti-Human CD19 Nanobody (SAA2078) [SAA2078] (HB996043) is a alpaca monoclonal antibody detecting CD19 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

同种型

VHH-8His-Cys-tag

克隆号

SAA2078

克隆类型

Monoclonal

靶标

B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19, CD19

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

P15391

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

B-lymphocyte antigen CD19 is a ~61 kDa protein. Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. CD19 is the therapeutic target of tafasitamab (Monjuvi).

1. Vanshylla, K. et al. (2018) Scientific reports 8, 4244. PMID: 29523808

2. Carter, RH. et al. (1992) Science (New York, N.Y.) 256, 105-7. PMID: 1373518

3. van Zelm, MC. et al. (2006) The New England journal of medicine 354, 1901-12. PMID: 16672701

4. de Rie, MA. et al. (1989) Cellular immunology 118, 368-81. PMID: 2463100

5. Wang, Y. et al. (2002) Immunity 17, 501-14. PMID: 12387743

6. Sato, S. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 159, 3278-87. PMID: 9317126

7. Buhl, AM. et al. (1997) The Journal of experimental medicine 186, 1897-910. PMID: 9382888

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human CD19 Nanobody (SAA2078)

参考文献

产品说明书

Anti-Human CD19 Recombinant Nanobody (SAA2078).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD19 Recombinant Nanobody (SAA2078) (HB996043)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD19 Recombinant Nanobody (SAA2078) (HB996043)

概述

图片

参考文献

产品说明书

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