Anti-Human FZD3/Frizzled-3 Recombinant Nanobody (SAA2318) (HC066013)

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50ug
100ug
1mg

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概述
图片
参考文献
产品说明书

概述

货号

HC066013

品牌

abinScience

描述

Anti-Human FZD3/Frizzled-3 Nanobody (SAA2318) [SAA2318] (HC066013) is a human monoclonal antibody detecting Frizzled-3 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Human

同种型

VHH-Fc

克隆号

SAA2318

克隆类型

Monoclonal

靶标

Frizzled-3, Fz-3, hFz3, FZD3

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

Q9NPG1

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Frizzled-3 (FZD3) is a ~76 kDa protein. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Activation by Wnt5A stimulates PKC activity via a G-protein-dependent mechanism.

Note

For research use only

图片

SDS-PAGE

SDS-PAGE for Anti-Human FZD3/Frizzled-3 Nanobody (SAA2318)

参考文献

产品说明书

Anti-Human FZD3/Frizzled-3 Recombinant Nanobody (SAA2318).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FZD3/Frizzled-3 Recombinant Nanobody (SAA2318) (HC066013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FZD3/Frizzled-3 Recombinant Nanobody (SAA2318) (HC066013)

概述

图片

参考文献

产品说明书

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