Anti-Mouse PD-L1 Recombinant Antibody (SAA0359), APC (MV974237)

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货号	MV974237
品牌	abinScience
种属反应性	Mouse
应用	ELISA, FCM, IF
宿主	Mouse
同种型	VHH, mFc
克隆号	SAA0359
偶联物	APC
克隆类型	Monoclonal
经测试应用	FCM
靶标	Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274, Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
内毒素水平	Please contact with the lab for this information.
相关产品	VHH-mFc Isotype Control antibody (cAb-Lys2), APC
Accession号	Q9EP73
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Programmed cell death 1 ligand 1 (CD274/PD-L1) is a ~32 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10). CD274 is the therapeutic target of atezolizumab (Tecentriq) and durvalumab (Imfinzi). 1. Tamura, H. et al. (2001) Blood 97, 1809-16. PMID: 11238124 2. Freeman, GJ. et al. (2000) The Journal of experimental medicine 192, 1027-34. PMID: 11015443 3. Wang, S. et al. (2003) The Journal of experimental medicine 197, 1083-91. PMID: 12719480
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Flow CytoMetry

Flow-cytometry using APC anti-mouse CD274 antibody. MDA-MB-231 cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-mouse CD274 monoclonal antibody (Catalog: MV974237, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Mouse PD-L1 Recombinant Antibody (SAA0359), APC.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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Anti-Mouse PD-L1 Recombinant Antibody (SAA0359), APC (MV974237)

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参考文献

产品说明书

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实验相关试剂

Anti-Mouse PD-L1 Recombinant Antibody (SAA0359), APC (MV974237)

概述

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参考文献

产品说明书

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