Anti-Human SSTR2 & CD3 epsilon Bispecific Reference Antibody (Tidutamab, RUO) (HB795016)

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概述

货号	HB795016
品牌	abinScience
描述	Tidutamab (HB795016) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG1-kappa/scFv-h-CH2-CH3
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	SRIF-1, SS2R, Somatostatin receptor type 2, SS-2-R, SS2-R, SSTR2, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P30874 & P07766
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Bispecific, XmAb-18087, 2148354-90-7
背景	Tidutamab (XmAb-18087) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and T-cell binding domain (CD3). Tidutamab possesses a full Fc domain to maintain long serum half-life.Tidutamab eliminates SSTR+ tumor cells by stimulating redirected T cellmediated cytotoxicity (RTcC).
Note	For research use only. Not suitable for clinical or therapeutic use.

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Flow CytoMetry

Flow-cytometry using anti-human SSTR2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human SSTR2 monoclonal antibody (Catalog: HB795016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
SDS-PAGE

SDS-PAGE for Research Grade Tidutamab
Flow cytometry

Flow-cytometry APC using anti-human SSTR2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human SSTR2 monoclonal antibody (Catalog HB795016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry PE using anti-human SSTR2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an PE anti-human SSTR2 monoclonal antibody (Catalog HB795016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry FITC using anti-human SSTR2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an FITC anti-human SSTR2 monoclonal antibody (Catalog HB795016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献

产品说明书

Anti-Human SSTR2 & CD3 epsilon Bispecific Reference Antibody (Tidutamab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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Anti-Human SSTR2 & CD3 epsilon Bispecific Reference Antibody (Tidutamab, RUO) (HB795016)

概述

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参考文献

产品说明书

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实验相关试剂

Anti-Human SSTR2 & CD3 epsilon Bispecific Reference Antibody (Tidutamab, RUO) (HB795016)

概述

图片

参考文献

产品说明书

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