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Anti-Human PD-L1 & CTLA-4 Bispecific Reference Antibody (Erfonrilimab, RUO) (HV974146)

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规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
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  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HV974146
品牌abinScience
描述
Erfonrilimab (HV974146) is a research-grade recombinant antibody targeting CD152. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型Single Domains (VH-VH'-CH), IgG1na;na
表达系统Mammalian cells
克隆类型Monoclonal
靶标CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4, B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P16410 & Q9NZQ7
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Bispecific, KN-046, KN046, 2367013-69-0
背景Erfonrilimab (KN-046) is an anti-PDL1/CTLA-4 monoclonal antibody.
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Bioactivity

    Detects CD274/PD-L1/B7-H1 in indirect ELISAs.

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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