货号 | HV612046 |
---|---|
品牌 | abinScience |
种属反应性 | Human |
应用 | Research Grade Biosimilar |
宿主 | Humanized |
同种型 | scFv with Domain Crossover,Kappa;Lambda |
表达系统 | Mammalian Cells |
克隆类型 | Monoclonal |
靶标 | CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
内毒素水平 | Please contact the lab for this information. |
纯度 | >95% purity as determined by SDS-PAGE. |
纯化方式 | Protein A/G, purified from cell culture supernatant. |
Accession号 | Q5ZPR3 & P07766 |
状态 | Liquid |
保存溶液 | 0.01M PBS,pH7.4. |
稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
别名 | Bispecific,MGD009,RES281M1.1,hBRCA84D-hXR32-MP3M1.1,CAS:2069959-72-2 |
背景 | Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer. |
Note | For research use only. Not for use in clinical or therapeutic applications. |
SDS-PAGE for Research Grade Obrindatamab
Detects CD276 in indirect ELISAs.
Detects CD3E in indirect ELISAs.
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