Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO) (YP862016)

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概述

货号	YP862016
品牌	abinScience
描述	Bavituximab (YP862016) is a research-grade recombinant antibody targeting Phosphatidylserine. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	General
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Chimeric
同种型	IgG1-kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	Phosphatidylserine
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	1446756-47-3
RRID	Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO) (abinScience Cat# YP862016, RRID:AB_3751823)
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名	Tarvacinch3 G4, CAS: 648904-28-3
背景	Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel and Carboplatin, have enhanced inhibition on non-small-cell lung cancer. • Phosphatidylserine and the human brain., PMID:25933483 • The distribution and function of phosphatidylserine in cellular membranes., PMID:20192774 • Phosphatidylserine transport in cell life and death., PMID:37413778 • Phosphatidylserine., PMID:10541030 • Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment., PMID:39456225 • Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis., PMID:33539192 • Phosphatidylserine externalization as immune checkpoint in cancer., PMID:38573347 • Phosphatidylserine: A comprehensive overview of synthesis, metabolism, and nutrition., PMID:39097133 • Dynamics of phagocytosis mediated by phosphatidylserine., PMID:36281986 • Flagging fusion: Phosphatidylserine signaling in cell-cell fusion., PMID:33581114
Note	For research use only. Not suitable for clinical or therapeutic use.

图片

Bioactivity

SEC-HPLC detection for Research Grade Bavituximab.
SDS-PAGE

SDS-PAGE for Research Grade Bavituximab

参考文献

Phosphatidylserine-everted erythrocyte membrane vesicles enhance efferocytosis and remodeling of vascular grafts

产品说明书

Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO) (YP862016)

概述

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参考文献

产品说明书

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实验相关试剂

Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO) (YP862016)

概述

图片

参考文献

产品说明书

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