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HEK293T Human CD112/Nectin-2/PVRL2 Stable Cell Line (HV456818)

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规格：
  • 1 ml
数量：
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概述
货号HV456818
品牌abinScience
描述
HEK293T Human CD112/Nectin-2/PVRL2 Stable Cell Line (HV456818) is a stable cell line expressing CD112/Nectin-2/PVRL2. Engineered for consistent, high-level target expression in research applications.
Highlights
  • ●Stable Expression — Engineered for consistent, high-level target expression.
Accession号Q92692
应用FCM
种属Human
靶标CD112/Nectin-2/PVRL2
性能Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
稳定性和存储Frozen in liquid nitrogen.
规格1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
背景

Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705
2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
图片

  • Flow cytometry

    Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD112 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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HEK293T Human CD112/Nectin-2/PVRL2 Stable Cell Line

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