Anti-Human MICA/B Recombinant Antibody (20C6) (HS894013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HS894013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

经测试应用

MICA, MIC-A, MHC class I polypeptide-related sequence A, PERB11.1, MIC-B, MHC class I polypeptide-related sequence B, MICB, PERB11.2

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q29983, Q29980

Anti-Human MICA/B Antibody (20C6) (abinScience Cat# HS894013, RRID:AB_3726911)
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Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

MHC class I polypeptide-related sequence A (MICA/MICB) is a ~42 kDa protein. Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8 alphabeta T-cells. Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production.

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1. Steinle, A. et al. (2001) Immunogenetics 53, 279-87. PMID: 11491531

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2. Sutherland, CL. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 671-9. PMID: 11777960

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3. Bauer, S. et al. (1999) Science (New York, N.Y.) 285, 727-9. PMID: 10426993

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human MICA/B Antibody (20C6).
Flow CytoMetry

Flow-cytometry using anti-human MICA antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human MICA monoclonal antibody (Catalog: HS894013) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Human MICA/B Recombinant Antibody (20C6).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human MICA/B Recombinant Antibody (20C6) (HS894013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human MICA/B Recombinant Antibody (20C6) (HS894013)

概述

图片

参考文献

产品说明书

相关产品推荐

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