Anti-Human TSPAN8 Recombinant Antibody (SAA1592) (HB737013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HB737013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1592

TSPAN8, Tspan-8, Tumor-associated antigen CO-029, TM4SF3, Transmembrane 4 superfamily member 3, Tetraspanin-8

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P19075

Anti-Human TSPAN8 Antibody (SAA1592) (abinScience Cat# HB737013, RRID:AB_3727353)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Tetraspanin-8 (TSPAN8) is a ~26 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, migration and protein trafficking. Promotes ADAM17-mediated TNF processing through recruitment of ADAM17 to tetraspanin-enriched micro-domains (TEMs). Forms a complex with RICTOR and integrin alpha3/ITGA3 to mediate mTORC2 activation and AKT1 phosphorylation leading to cell migration. Reduces apoptosis and autophagy induced by high glucose levels through forming a complex with mTOR and RICTOR.

1. Schmidt, F. et al. (2016) Biological chemistry. PMID: 27180357

2. Müller, M. et al. (2022) Cells 11. PMID: 36078095

3. Pan, SJ. et al. (2015) International journal of molecular sciences 16, 5363-74. PMID: 25761241

4. Zhuang, L. et al. (2022) Cell biology international 46, 1693-1703. PMID: 35904232

5. Min, J. et al. (2023) Cellular and molecular life sciences : CMLS 80, 154. PMID: 37204469

6. Zhu, Y. et al. (2023) Cancers 15. PMID: 37835445

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human TSPAN8 Antibody (SAA1592)

产品说明书

Anti-Human TSPAN8 Recombinant Antibody (SAA1592).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TSPAN8 Recombinant Antibody (SAA1592) (HB737013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TSPAN8 Recombinant Antibody (SAA1592) (HB737013)

概述

图片

参考文献

产品说明书

相关产品推荐

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