Anti-Human LTK Recombinant Antibody (SAA1618) (HB966013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HB966013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1618

TYK1, Leukocyte tyrosine kinase receptor, LTK, Protein tyrosine kinase 1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P29376

Anti-Human LTK Antibody (SAA1618) (abinScience Cat# HB966013, RRID:AB_3727379)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Leukocyte tyrosine kinase receptor (LTK) is a ~91 kDa protein. Receptor with a tyrosine-protein kinase activity. Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response. Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase (MAPK) pathway. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif. The exact function of this protein is not known; studies with chimeric proteins demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival.

1. Honda, H. et al. (1999) Oncogene 18, 3821-30. PMID: 10445845

2. Farhan, H. et al. (2010) The Journal of cell biology 189, 997-1011. PMID: 20548102

3. Reshetnyak, AV. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 8340-8345. PMID: 30061385

4. De Munck, S. et al. (2021) Nature 600, 143-147. PMID: 34646012

5. Yamada, S. et al. (2008) Neuroreport 19, 1733-8. PMID: 18849880

6. Ueno, H. et al. (1997) Oncogene 14, 3067-72. PMID: 9223670

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human LTK Antibody (SAA1618)

产品说明书

Anti-Human LTK Recombinant Antibody (SAA1618).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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试剂盒

实验相关试剂

Anti-Human LTK Recombinant Antibody (SAA1618) (HB966013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LTK Recombinant Antibody (SAA1618) (HB966013)

概述

图片

参考文献

产品说明书

相关产品推荐

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