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Anti-Human CHD4 IP Recombinant Antibody (SAA0262) (HC562013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HC562013
品牌abinScience
种属反应性Human
应用ELISA, IF, IP
宿主Mouse
克隆类型Monoclonal
同种型IgG2a
克隆号SAA0262
靶标CHD4, Mi2-beta, Chromodomain-helicase-DNA-binding protein 4, CHD-4, Mi-2 autoantigen 218 kDa protein, ATP-dependent helicase CHD4
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q14839
RRIDAnti-Human CHD4 IP Antibody (SAA0262) (abinScience Cat# HC562013, RRID:AB_3729796)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

ATP-dependent chromatin remodeler CHD4 is a ~218 kDa protein. ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis.

1. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666
2. Farnung, L. et al. (2020) eLife 9. PMID: 32543371
3. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440
4. Sillibourne, JE. et al. (2007) Molecular biology of the cell 18, 3667-80. PMID: 17626165
5. Tong, JK. et al. (1998) Nature 395, 917-21. PMID: 9804427
6. Gong, F. et al. (2015) Genes & development 29, 197-211. PMID: 25593309
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CHD4 IP Antibody (SAA0262)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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