Anti-Human Hepcidin Recombinant Antibody (SAA2724) (HX911013)

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1mg

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货号	HX911013
品牌	abinScience
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Mouse
克隆类型	Monoclonal
同种型	IgG2a, kappa
克隆号	SAA2724
靶标	HAMP, HEPC, Hepc20, Hepc25, Hepcidin, Hepcidin-20, Hepcidin-25, LEAP-1, LEAP1, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor
内毒素水平	<10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P81172
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Hepcidin is a ~9 kDa protein. Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes. 1. Qiao, B. et al. (2012) Cell metabolism 15, 918-24. PMID: 22682227 2. Aschemeyer, S. et al. (2018) Blood 131, 899-910. PMID: 29237594 3. Billesbølle, CB. et al. (2020) Nature 586, 807-811. PMID: 32814342 4. Ganz, T. et al. (2012) Biochimica et biophysica acta 1823, 1434-43. PMID: 22306005
Note	For research use only

产品说明书

Anti-Human Hepcidin Recombinant Antibody (SAA2724).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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Anti-Human Hepcidin Recombinant Antibody (SAA2724) (HX911013)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Hepcidin Recombinant Antibody (SAA2724) (HX911013)

概述

图片

参考文献

产品说明书

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