Anti-CAV1 Polyclonal Antibody (HX089014)

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概述
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产品说明书

概述

货号

HX089014

品牌

abinScience

描述

Anti-CAV1 Polyclonal Antibody (HX089014) is a rabbit polyclonal antibody detecting CAV1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Cat, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CAV1 (Ser2-Ser104).

靶标

CAV, CAV1, Caveolin-1

纯化方式

Purified by antigen affinity column.

Accession号

Q03135

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Caveolin-1 (CAV1) is a ~20 kDa protein. May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.

1. Vargas, L. et al. (2002) The Journal of biological chemistry 277, 9351-7. PMID: 11751885

2. McMahon, KA. et al. (2009) The EMBO journal 28, 1001-15. PMID: 19262564

3. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217

4. Hwangbo, C. et al. (2016) Oncogene 35, 389-401. PMID: 25893292

Note

For research use only.

图片

参考文献

产品说明书

Anti-CAV1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CAV1 Polyclonal Antibody (HX089014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CAV1 Polyclonal Antibody (HX089014)

概述

图片

参考文献

产品说明书

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