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Anti-Human CAV1 Monoclonal Antibody (1A514) (HX089015)

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概述
货号HX089015
品牌abinScience
描述
Anti-Human CAV1 Monoclonal Antibody (1A514) [1A514] (HX089015) is a mouse monoclonal antibody detecting CAV1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Mouse
同种型IgG
克隆号1A514
克隆类型Monoclonal
免疫原E. coli - derived recombinant human CAV1 (Met1-Ser104).
靶标Caveolin-1, CAV1
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q03135
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Caveolin-1 (CAV1) is a ~20 kDa protein. May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.

1. Vargas, L. et al. (2002) The Journal of biological chemistry 277, 9351-7. PMID: 11751885
2. McMahon, KA. et al. (2009) The EMBO journal 28, 1001-15. PMID: 19262564
3. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217
4. Hwangbo, C. et al. (2016) Oncogene 35, 389-401. PMID: 25893292
NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Anti-Human CAV1 Monoclonal Antibody (1A514)

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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