Anti-C1QBP Polyclonal Antibody (HC372014) is a rabbit polyclonal antibody detecting C1QBP in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.
种属反应性
Human
应用
ELISA, IHC, WB
宿主
Rabbit
同种型
IgG
克隆类型
Polyclonal
免疫原
E. coli - derived recombinant Human C1QBP (Thr76-Gln282).
靶标
Hyaluronan-binding protein 1, SF2AP32, C1QBP, gC1q-R protein, SF2P32, Glycoprotein gC1qBP, Complement component 1 Q subcomponent-binding protein, mitochondrial, ASF/SF2-associated protein p32, GC1QBP, HABP1, p33, C1qBP, Mitochondrial matrix protein p32
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
产品使用信息
应用方法
稀释比例
ELISA
1:5000-1:20000
IHC
1:50-1:500
WB
1:500-1:2000
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) is a ~31 kDa protein. Multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, protein synthesis in mitochondria, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. At the cell surface is thought to act as an endothelial receptor for plasma proteins of the complement and kallikrein-kinin cascades. Putative receptor for C1q; specifically binds to the globular 'heads' of C1q thus inhibiting C1; may perform the receptor function through a complex with C1qR/CD93. In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK. Can also bind other plasma proteins, such as coagulation factor XII leading to its autoactivation.
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