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Anti-CD91/LRP1 Polyclonal Antibody (HC475014)

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概述
货号HC475014
品牌abinScience
描述
Anti-CD91/LRP1 Polyclonal Antibody (HC475014) is a rabbit polyclonal antibody detecting LRP1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CD91/LRP1 (Ala20-His280).
靶标APOER, LRP1, LRP-1, LRP-515, LRP-85, A2MR, Prolow-density lipoprotein receptor-related protein 1, Apolipoprotein E receptor, APR, CD91, LRPICD, Alpha-2-macroglobulin receptor
纯化方式Purified by antigen affinity column.
Accession号Q07954
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Prolow-density lipoprotein receptor-related protein 1 (CD91/LRP1) is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor.

1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044
2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657
3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392
4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438
5. Rauch, JN. et al. (2020) Nature 580, 381-385. PMID: 32296178
6. Kinoshita, A. et al. (2003) The Journal of biological chemistry 278, 41182-8. PMID: 12888553
7. Leal, SM. et al. (1997) The Journal of biological chemistry 272, 20572-6. PMID: 9252371
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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