Human CD91/LRP1 Recombinant Protein (C-Fc) (HC475011)
概述
图片
参考文献
产品说明书
概述
货号
HC475011
品牌
abinScience
描述
Recombinant Human CD91/LRP1 Protein, C-Fc (HC475011) expressed in Mammalian Cells, spanning Arg786-Leu1165. Purity: >90% by SDS-PAGE.
Highlights
●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
●Mammalian Expression — Proper folding and native glycosylation.
●High Purity — >90% purity verified by SDS-PAGE.
表达系统
Mammalian cells
Accession号
Q07954
蛋白长度
Arg786-Leu1165
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
69.85 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
A2MR, APOER, APR, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, CD91, LRP-1, LRP-515, LRP-85, LRP1, LRPICD, Low-density lipoprotein receptor-related protein 1 515 kDa subunit, Low-density lipoprotein receptor-related protein 1 85 kDa subunit, Low-density lipoprotein receptor-related protein 1 intracellular domain, Prolow-density lipoprotein receptor-related protein 1
背景
Prolow-density lipoprotein receptor-related protein 1 is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor.
1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044
2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657
3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392
4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438
