

| 货号 | HC322014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-PPID Polyclonal Antibody (HC322014) is a rabbit polyclonal antibody detecting PPID in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, and Rat.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human PPID (Gln7-Pro206). | ||||||||
| 靶标 | Rotamase D, 40 kDa peptidyl-prolyl cis-trans isomerase, PPID, Cyclophilin-40, Peptidyl-prolyl cis-trans isomerase D, PPIase D, CYP40, CYP-40, Cyclophilin-related protein, CYPD | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q08752 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Peptidyl-prolyl cis-trans isomerase D (PPID) is a ~40 kDa protein. PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. 1. Pirkl, F. et al. (2001) Journal of molecular biology 308, 795-806. PMID: 11350175 2. Davis, TL. et al. (2010) PLoS biology 8, e1000439. PMID: 20676357 | ||||||||
| Note | For research use only. |

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