

| 货号 | PTX19764 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-PPID Polyclonal Antibody (PTX19764) is a rabbit polyclonal antibody detecting Rotamase D,40 kDa peptidyl-prolyl cis-trans isomerase,PPID,Cyclophilin-40,Peptidyl-prolyl cis-trans isomerase D,PPIase D,CYP40,CYP-40,Cyclophilin-related protein,CYPD in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human PPID (Gln7-Pro206). |
| 靶标 | Rotamase D,40 kDa peptidyl-prolyl cis-trans isomerase,PPID,Cyclophilin-40,Peptidyl-prolyl cis-trans isomerase D,PPIase D,CYP40,CYP-40,Cyclophilin-related protein,CYPD |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q08752 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Peptidyl-prolyl cis-trans isomerase D (PPID) is a ~40 kDa protein. PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. 1. Pirkl, F. et al. (2001) Journal of molecular biology 308, 795-806. PMID: 11350175 2. Davis, TL. et al. (2010) PLoS biology 8, e1000439. PMID: 20676357 |
| Note | For research use only. |

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