Anti-IL24 Polyclonal Antibody (HC472014)

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概述
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产品说明书

概述

货号

HC472014

品牌

abinScience

描述

Anti-IL24 Polyclonal Antibody (HC472014) is a rabbit polyclonal antibody detecting IL24 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human IL24 (Gln52-Leu206).

靶标

MDA7, MDA-7, ST16, IL-24, Melanoma differentiation-associated gene 7 protein, Suppression of tumorigenicity 16 protein, IL24, Interleukin-24

纯化方式

Purified by antigen affinity column.

Accession号

Q13007

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Interleukin-24 (IL24) is a ~23 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal.

1. Jin, SH. et al. (2014) Toxicology and applied pharmacology 280, 199-206. PMID: 25168428

2. Seong, RK. et al. (2016) Journal of microbiology (Seoul, Korea) 54, 695-700. PMID: 27687232

3. Wang, M. et al. (2002) The Journal of biological chemistry 277, 7341-7. PMID: 11706020

4. Lubkowski, J. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 201, 2082-2093. PMID: 30111632

Note

For research use only.

图片

参考文献

产品说明书

Anti-IL24 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-IL24 Polyclonal Antibody (HC472014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-IL24 Polyclonal Antibody (HC472014)

概述

图片

参考文献

产品说明书

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