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Anti-IL24 Polyclonal Antibody (PTX19432)

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概述
货号PTX19432
品牌ProteoGenix
描述
Anti-IL24 Polyclonal Antibody (PTX19432) is a rabbit polyclonal antibody detecting MDA7,MDA-7,ST16,IL-24,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein,IL24,Interleukin-24 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human IL24 (Gln52-Leu206).
靶标MDA7,MDA-7,ST16,IL-24,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein,IL24,Interleukin-24
纯化方式Purified by antigen affinity column.
Accession号Q13007
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interleukin-24 (IL24) is a ~23 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal.

1. Jin, SH. et al. (2014) Toxicology and applied pharmacology 280, 199-206. PMID: 25168428
2. Seong, RK. et al. (2016) Journal of microbiology (Seoul, Korea) 54, 695-700. PMID: 27687232
3. Wang, M. et al. (2002) The Journal of biological chemistry 277, 7341-7. PMID: 11706020
4. Lubkowski, J. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 201, 2082-2093. PMID: 30111632
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-IL24 Polyclonal Antibody

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