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Anti-CD150/SLAMF1 Polyclonal Antibody (HC275014)

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概述
货号HC275014
品牌abinScience
描述
Anti-CD150/SLAMF1 Polyclonal Antibody (HC275014) is a rabbit polyclonal antibody detecting SLAMF1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CD150/SLAMF1 (Phe19-Lys236).
靶标SLAM family member 1, IPO-3, CDw150, SLAMF1, SLAM, CD150, Signaling lymphocytic activation molecule
纯化方式Purified by antigen affinity column.
Accession号Q13291
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Signaling lymphocytic activation molecule (CD150/SLAMF1) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

1. Howie, D. et al. (2002) Blood 99, 957-65. PMID: 11806999
2. Li, C. et al. (2003) The Journal of biological chemistry 278, 3852-9. PMID: 12458214
3. Réthi, B. et al. (2006) Blood 107, 2821-9. PMID: 16317102
4. Yurchenko, MY. et al. (2010) Immunology and cell biology 88, 565-74. PMID: 20231852
5. Berger, SB. et al. (2010) Nature immunology 11, 920-7. PMID: 20818396
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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