

| 货号 | HC275013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1581 | ||||
| 靶标 | SLAM family member 1, IPO-3, CDw150, SLAMF1, SLAM, CD150, Signaling lymphocytic activation molecule | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q13291 | ||||
| RRID | Anti-Human CD150/SLAMF1 Antibody (SAA1581) (abinScience Cat# HC275013, RRID:AB_3727342) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||
| 产品使用信息 |
| ||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Signaling lymphocytic activation molecule (CD150/SLAMF1) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. 1. Howie, D. et al. (2002) Blood 99, 957-65. PMID: 11806999 2. Li, C. et al. (2003) The Journal of biological chemistry 278, 3852-9. PMID: 12458214 3. Réthi, B. et al. (2006) Blood 107, 2821-9. PMID: 16317102 4. Yurchenko, MY. et al. (2010) Immunology and cell biology 88, 565-74. PMID: 20231852 5. Berger, SB. et al. (2010) Nature immunology 11, 920-7. PMID: 20818396 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human CD150/SLAMF1 Antibody (SAA1581)



24小时产品查询

扫一扫关注我们

专属渠道经理