Anti-CD218a/IL18R1 Polyclonal Antibody (HC691014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HC691014

品牌

abinScience

描述

Anti-CD218a/IL18R1 Polyclonal Antibody (HC691014) is a rabbit polyclonal antibody detecting CD218a in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CD218a/IL18R1 (Thr147-Asn255).

靶标

CD218a, IL-18R1, IL18R1, CDw218a, IL-18R-alpha, IL-18R-1, Interleukin-18 receptor 1, IL-18Ralpha, IL1 receptor-related protein, CD218 antigen-like family member A, IL-1Rrp, IL1RRP, IL1R-rp, Interleukin-18 receptor alpha

纯化方式

Purified by antigen affinity column.

Accession号

Q13478

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Interleukin-18 receptor 1 (CD218a/IL18R1) is a ~62 kDa protein. Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.

1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293

2. Wei, H. et al. (2014) FEBS letters 588, 3838-43. PMID: 25261253

3. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532

4. Shi, X. et al. (2023) Nature 624, 442-450. PMID: 37993714

5. Parnet, P. et al. (1996) The Journal of biological chemistry 271, 3967-70. PMID: 8626725

6. Tominaga, K. et al. (2000) International immunology 12, 151-60. PMID: 10653850

Note

For research use only.

图片

参考文献

产品说明书

Anti-CD218a/IL18R1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD218a/IL18R1 Polyclonal Antibody (HC691014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CD218a/IL18R1 Polyclonal Antibody (HC691014)

概述

图片

参考文献

产品说明书

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