Anti-ENPP2 Polyclonal Antibody (HC423014)

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概述
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参考文献
产品说明书

概述

货号

HC423014

品牌

abinScience

描述

Anti-ENPP2 Polyclonal Antibody (HC423014) is a rabbit polyclonal antibody detecting ENPP2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human ENPP2 (Ser637-Ile863).

靶标

LysoPLD, Extracellular lysophospholipase D, ENPP2, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, PDNP2, Autotaxin, ATX

纯化方式

Purified by antigen affinity column.

Accession号

Q13822

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Autotaxin (ENPP2) is a ~98 kDa protein. Secreted lysophospholipase D that hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids. Its major substrate is lysophosphatidylcholine. Can also act on sphingosylphosphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth.

1. Aoki, J. et al. (2002) The Journal of biological chemistry 277, 48737-44. PMID: 12354767

2. Clair, T. et al. (2003) Cancer research 63, 5446-53. PMID: 14500380

3. van Meeteren, LA. et al. (2005) The Journal of biological chemistry 280, 21155-61. PMID: 15769751

4. Stein, AJ. et al. (2015) Molecular pharmacology 88, 982-92. PMID: 26371182

5. Bain, G. et al. (2017) The Journal of pharmacology and experimental therapeutics 360, 1-13. PMID: 27754931

6. Tokumura, A. et al. (2002) The Journal of biological chemistry 277, 39436-42. PMID: 12176993

9. Bolen, AL. et al. (2011) Journal of lipid research 52, 958-70. PMID: 21393252

Note

For research use only.

图片

参考文献

产品说明书

Anti-ENPP2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ENPP2 Polyclonal Antibody (HC423014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ENPP2 Polyclonal Antibody (HC423014)

概述

图片

参考文献

产品说明书

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