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Anti-ENPP2 Polyclonal Antibody (PTX19779)

概述
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参考文献

概述

货号	PTX19779
品牌	ProteoGenix
描述	Anti-ENPP2 Polyclonal Antibody (PTX19779) is a rabbit polyclonal antibody detecting LysoPLD,Extracellular lysophospholipase D,ENPP2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2,E-NPP 2,PDNP2,Autotaxin,ATX in ELISA, IHC, WB. Suitable for Human, Mouse, Rat. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Rat
应用	ELISA, IHC, WB
宿主	Rabbit
同种型	IgG
克隆类型	Polyclonal
免疫原	E. coli - derived recombinant Human ENPP2 (Ser637-Ile863).
靶标	LysoPLD,Extracellular lysophospholipase D,ENPP2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2,E-NPP 2,PDNP2,Autotaxin,ATX
纯化方式	Purified by antigen affinity column.
Accession号	Q13822
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Autotaxin (ENPP2) is a ~98 kDa protein. Secreted lysophospholipase D that hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids. Its major substrate is lysophosphatidylcholine. Can also act on sphingosylphosphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. 1. Aoki, J. et al. (2002) The Journal of biological chemistry 277, 48737-44. PMID: 12354767 2. Clair, T. et al. (2003) Cancer research 63, 5446-53. PMID: 14500380 3. van Meeteren, LA. et al. (2005) The Journal of biological chemistry 280, 21155-61. PMID: 15769751 4. Stein, AJ. et al. (2015) Molecular pharmacology 88, 982-92. PMID: 26371182 5. Bain, G. et al. (2017) The Journal of pharmacology and experimental therapeutics 360, 1-13. PMID: 27754931 6. Tokumura, A. et al. (2002) The Journal of biological chemistry 277, 39436-42. PMID: 12176993 9. Bolen, AL. et al. (2011) Journal of lipid research 52, 958-70. PMID: 21393252
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-ENPP2 Polyclonal Antibody

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