Anti-BMPR2 Polyclonal Antibody (HC650014)

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概述
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参考文献
产品说明书

概述

货号

HC650014

品牌

abinScience

描述

Anti-BMPR2 Polyclonal Antibody (HC650014) is a rabbit polyclonal antibody detecting BMPR2 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human BMPR2 (Ser27-Thr150).

靶标

BMP type II receptor, BMPR-II, Bone morphogenetic protein receptor type II, Bone morphogenetic protein receptor type-2, BMPR2, PPH1, BMP type-2 receptor, BMPR-2

纯化方式

Purified by antigen affinity column.

Accession号

Q13873

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Bone morphogenetic protein receptor type-2 (BMPR2) is a ~115 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Can also mediate signaling through the activation of the p38MAPK cascade. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs.

1. Rudarakanchana, N. et al. (2002) Human molecular genetics 11, 1517-25. PMID: 12045205

2. Rejon, CA. et al. (2013) Cellular signalling 25, 2717-26. PMID: 24018044

Note

For research use only.

图片

参考文献

产品说明书

Anti-BMPR2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-BMPR2 Polyclonal Antibody (HC650014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-BMPR2 Polyclonal Antibody (HC650014)

概述

图片

参考文献

产品说明书

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