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Anti-BMPR2 Polyclonal Antibody (PTX19780)

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概述
货号PTX19780
品牌ProteoGenix
描述
Anti-BMPR2 Polyclonal Antibody (PTX19780) is a rabbit polyclonal antibody detecting BMP type II receptor,BMPR-II,Bone morphogenetic protein receptor type II,Bone morphogenetic protein receptor type-2,BMPR2,PPH1,BMP type-2 receptor,BMPR-2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human BMPR2 (Ser27-Thr150).
靶标BMP type II receptor,BMPR-II,Bone morphogenetic protein receptor type II,Bone morphogenetic protein receptor type-2,BMPR2,PPH1,BMP type-2 receptor,BMPR-2
纯化方式Purified by antigen affinity column.
Accession号Q13873
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Bone morphogenetic protein receptor type-2 (BMPR2) is a ~115 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Can also mediate signaling through the activation of the p38MAPK cascade. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs.

1. Rudarakanchana, N. et al. (2002) Human molecular genetics 11, 1517-25. PMID: 12045205
2. Rejon, CA. et al. (2013) Cellular signalling 25, 2717-26. PMID: 24018044
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-BMPR2 Polyclonal Antibody

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