Anti-TRADD Polyclonal Antibody (HS785014)

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概述
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参考文献
产品说明书

概述

货号

HS785014

品牌

abinScience

描述

Anti-TRADD Polyclonal Antibody (HS785014) is a rabbit polyclonal antibody detecting TRADD in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human TRADD (Met61-Leu297).

靶标

TRADD, TNFR1-associated DEATH domain protein, Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFRSF1A-associated via death domain

纯化方式

Purified by antigen affinity column.

Accession号

Q15628

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) is a ~34 kDa protein. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.

1. Li, S. et al. (2013) Nature 501, 242-6. PMID: 23955153

2. Hsu, H. et al. (1995) Cell 81, 495-504. PMID: 7758105

3. Hsu, H. et al. (1996) Immunity 4, 387-96. PMID: 8612133

Note

For research use only.

图片

参考文献

产品说明书

Anti-TRADD Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-TRADD Polyclonal Antibody (HS785014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-TRADD Polyclonal Antibody (HS785014)

概述

图片

参考文献

产品说明书

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