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Anti-FSCN1 Polyclonal Antibody (HS760014)

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概述
货号HS760014
品牌abinScience
描述
Anti-FSCN1 Polyclonal Antibody (HS760014) is a rabbit polyclonal antibody detecting FSCN1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human FSCN1 (Gln277-Gly396).
靶标SNL, FAN1, Fascin, 55 kDa actin-bundling protein, p55, Singed-like protein, FSCN1, HSN
纯化方式Purified by antigen affinity column.
Accession号Q16658
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Fascin (FSCN1) is a ~54 kDa protein. Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF.

1. Jansen, S. et al. (2011) The Journal of biological chemistry 286, 30087-96. PMID: 21685497
2. Yang, S. et al. (2013) The Journal of biological chemistry 288, 274-84. PMID: 23184945
3. Chen, L. et al. (2010) Nature 464, 1062-6. PMID: 20393565
4. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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