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Anti-Human FSCN1 Monoclonal Antibody (1A595) (HS760025)

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概述
货号HS760025
品牌abinScience
描述
Anti-Human FSCN1 Monoclonal Antibody (1A595) [1A595] (HS760025) is a mouse monoclonal antibody detecting FSCN1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Mouse
同种型IgG
克隆号1A595
克隆类型Monoclonal
免疫原E. coli - derived recombinant human FSCN1 (Gln277-Gly396).
靶标Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55, FSCN1
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q16658
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Fascin (FSCN1) is a ~54 kDa protein. Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF.

1. Jansen, S. et al. (2011) The Journal of biological chemistry 286, 30087-96. PMID: 21685497
2. Yang, S. et al. (2013) The Journal of biological chemistry 288, 274-84. PMID: 23184945
3. Chen, L. et al. (2010) Nature 464, 1062-6. PMID: 20393565
4. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786
NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Anti-Human FSCN1 Monoclonal Antibody (1A595)

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human FSCN1 Monoclonal Antibody (1A595)

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