Anti-TIM-3 Polyclonal Antibody (HV029014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HV029014

品牌

abinScience

描述

Anti-CD366/HAVCR2/TIM-3 Polyclonal Antibody (HV029014) is a rabbit polyclonal antibody detecting HAVCR2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CD366/HAVCR2/TIM-3 (Ser22-Arg200).

靶标

T-cell immunoglobulin mucin receptor 3, HAVcr-2, TIMD-3, T-cell membrane protein 3, HAVCR2, Hepatitis A virus cellular receptor 2, CD366, TIMD3, TIM-3, TIM3, T-cell immunoglobulin and mucin domain-containing protein 3

纯化方式

Purified by antigen affinity column.

Accession号

Q8TDQ0

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Hepatitis A virus cellular receptor 2 (CD366/TIM-3) is a ~33 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

1. Gorman, JV. et al. (2014) Immunologic research 59, 56-65. PMID: 24825777

2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861

3. Sánchez-Fueyo, A. et al. (2003) Nature immunology 4, 1093-101. PMID: 14556005

4. Clayton, KL. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 782-91. PMID: 24337741

5. Tomkowicz, B. et al. (2015) PloS one 10, e0140694. PMID: 26492563

6. Gautron, AS. et al. (2014) European journal of immunology 44, 2703-2711. PMID: 24838857

7. Zhu, C. et al. (2005) Nature immunology 6, 1245-52. PMID: 16286920

8. Leitner, J. et al. (2013) PLoS pathogens 9, e1003253. PMID: 23555261

9. Gleason, MK. et al. (2012) Blood 119, 3064-72. PMID: 22323453

Note

For research use only.

图片

参考文献

产品说明书

Anti-TIM-3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-TIM-3 Polyclonal Antibody (HV029014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-TIM-3 Polyclonal Antibody (HV029014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价