Anti-SIGLEC10 Polyclonal Antibody (HV244014)

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概述
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参考文献
产品说明书

概述

货号

HV244014

品牌

abinScience

描述

Anti-SIGLEC10 Polyclonal Antibody (HV244014) is a rabbit polyclonal antibody detecting SIGLEC10 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human SIGLEC10 (Met571-Gln697).

靶标

SIGLEC10, Siglec-10, Sialic acid-binding Ig-like lectin 10, Siglec-like protein 2, SLG2

纯化方式

Purified by antigen affinity column.

Accession号

Q96LC7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Sialic acid-binding Ig-like lectin 10 (SIGLEC10/SLG2) is a ~76 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, seems to act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Involved in negative regulation of B-cell antigen receptor signaling.

1. Munday, J. et al. (2001) The Biochemical journal 355, 489-97. PMID: 11284738

2. Kitzig, F. et al. (2002) Biochemical and biophysical research communications 296, 355-62. PMID: 12163025

3. Zhang, P. et al. (2015) The Journal of surgical research 194, 107-13. PMID: 25450598

Note

For research use only.

图片

参考文献

产品说明书

Anti-SIGLEC10 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SIGLEC10 Polyclonal Antibody (HV244014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SIGLEC10 Polyclonal Antibody (HV244014)

概述

图片

参考文献

产品说明书

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